The Intervention Reduced The Signs Of Levels Of Inflammation In Their Lungs, Which Is A Risk Factor For Developing Asthma.
And asthma is really an immune allergic-type reaction in the lungs,” Finlay says. “And so our best guess is the way these microbes are working is they are influencing how our immune system is shaped really early in life.” To further test their theory, the researchers gave laboratory mice bred to have a condition resembling asthma in humans the four missing microbes. The intervention reduced the signs of levels of inflammation in their lungs, which is a risk factor for developing asthma. The bacteria are from four genuses: Lachnospira, Veillonella, Faecalibacterium and Rothia. The researchers aren’t exactly sure how the microbes may protect against asthma. But babies with few or none of them had low levels of a substance known as acetate, which is believed to be involved with regulating the immune system. Other scientists praised the work and said it provided additional evidence about how important it is for kids to get the right microbes in the first few months after birth. “The microbes that babies have early in life are not accidental. They got a lot of them from their mothers.
For the original version including any supplementary images or video, visit http://www.npr.org/sections/health-shots/2015/09/30/444746094/missing-microbes-provide-clues-about-asthma-risk?utm_medium=RSS&utm_campaign=morningedition